Principal/Senior Scientist, Computational Chemistry
Avaron AB
📍 Göteborg
⏰ Heltid
📋 Vanlig anställning
🗓 Ansök senast 9 maj 2026
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About the Company
Avaron helps you find assignments that match your skills and ambitions. As a permanently employed consultant with us, you get competitive terms – combined with the variety and growth that a consulting career offers.
About the Assignment
You will step into a key role in a biopharma research environment where computational chemistry is central to advancing drug discovery. In this assignment, you will work across multiple projects in the portfolio and help teams make better decisions around molecular design, prediction, and SAR analysis. Your work will contribute to improving potency, selectivity, activity, and ADMET properties in drug compounds.
You will collaborate closely with medicinal chemists and other specialists throughout the discovery process, combining computational chemistry and AI approaches to support project delivery. The environment is highly cross-functional and brings together expertise in cheminformatics, molecular simulations, structure- and ligand-based design, machine learning, and model development. You will also contribute to identifying scientific improvement areas and evaluating how new methods can be applied in ongoing research. This is an exciting opportunity to work at the intersection of advanced modelling, drug discovery, and scientific innovation, with access to modern software and high-performance computing resources.
Job DescriptionYou will apply computational chemistry methods and AI approaches to support molecular design and predictive modelling across drug discovery projects.
You will perform SAR analysis and generate insights that help improve potency, selectivity, activity, and ADMET properties.
You will work closely with medicinal chemists and multidisciplinary teams across different discovery phases.
You will evaluate and introduce new scientific approaches within computational sciences and assess their value for project delivery.
You will collaborate with internal colleagues and external partners to strengthen computational capabilities and ways of working.
You will contribute in an environment that spans cheminformatics, molecular simulations, structure- and ligand-based design, machine learning, and model development.
You will stay current with literature and developments in the field and may contribute to original research and scientific reviews.
RequirementsPhD, or equivalent experience, in computational chemistry or a related field such as chemistry or pharmacology, with a strong computational background.
Solid knowledge of drug discovery concepts and a strong understanding of how computational chemistry contributes to project delivery.
Proven experience applying computational chemistry techniques with measurable impact in drug discovery.
Deep knowledge of structure-based drug design techniques, especially molecular dynamics and/or modern FEP methods.
Knowledge of scientific computing and programming skills in one or more of the following: Python, Perl, C, C++, Java, or R.
Good understanding of the wider drug discovery process and adjacent disciplines such as synthetic, structural and medicinal chemistry, DMPK, structural biology, biophysics, and biological science.
Strong written and verbal communication skills and the ability to collaborate effectively in multidisciplinary teams.
Strong planning skills, good time management, and a clear delivery focus.
Nice to haveExperience with ligand-based design techniques.
Experience in machine learning and cheminformatics.
What We OfferPermanent employment at Avaron AB
Occupational pension
Wellness allowance of SEK 5,000 per year
Application
Selections are made on an ongoing basis – apply as soon as you can.
Avaron helps you find assignments that match your skills and ambitions. As a permanently employed consultant with us, you get competitive terms – combined with the variety and growth that a consulting career offers.
About the Assignment
You will step into a key role in a biopharma research environment where computational chemistry is central to advancing drug discovery. In this assignment, you will work across multiple projects in the portfolio and help teams make better decisions around molecular design, prediction, and SAR analysis. Your work will contribute to improving potency, selectivity, activity, and ADMET properties in drug compounds.
You will collaborate closely with medicinal chemists and other specialists throughout the discovery process, combining computational chemistry and AI approaches to support project delivery. The environment is highly cross-functional and brings together expertise in cheminformatics, molecular simulations, structure- and ligand-based design, machine learning, and model development. You will also contribute to identifying scientific improvement areas and evaluating how new methods can be applied in ongoing research. This is an exciting opportunity to work at the intersection of advanced modelling, drug discovery, and scientific innovation, with access to modern software and high-performance computing resources.
Job DescriptionYou will apply computational chemistry methods and AI approaches to support molecular design and predictive modelling across drug discovery projects.
You will perform SAR analysis and generate insights that help improve potency, selectivity, activity, and ADMET properties.
You will work closely with medicinal chemists and multidisciplinary teams across different discovery phases.
You will evaluate and introduce new scientific approaches within computational sciences and assess their value for project delivery.
You will collaborate with internal colleagues and external partners to strengthen computational capabilities and ways of working.
You will contribute in an environment that spans cheminformatics, molecular simulations, structure- and ligand-based design, machine learning, and model development.
You will stay current with literature and developments in the field and may contribute to original research and scientific reviews.
RequirementsPhD, or equivalent experience, in computational chemistry or a related field such as chemistry or pharmacology, with a strong computational background.
Solid knowledge of drug discovery concepts and a strong understanding of how computational chemistry contributes to project delivery.
Proven experience applying computational chemistry techniques with measurable impact in drug discovery.
Deep knowledge of structure-based drug design techniques, especially molecular dynamics and/or modern FEP methods.
Knowledge of scientific computing and programming skills in one or more of the following: Python, Perl, C, C++, Java, or R.
Good understanding of the wider drug discovery process and adjacent disciplines such as synthetic, structural and medicinal chemistry, DMPK, structural biology, biophysics, and biological science.
Strong written and verbal communication skills and the ability to collaborate effectively in multidisciplinary teams.
Strong planning skills, good time management, and a clear delivery focus.
Nice to haveExperience with ligand-based design techniques.
Experience in machine learning and cheminformatics.
What We OfferPermanent employment at Avaron AB
Occupational pension
Wellness allowance of SEK 5,000 per year
Application
Selections are made on an ongoing basis – apply as soon as you can.